PRODUCT DETAILS

About Atorec R 5mg/10mg Capsule

ATORVASTATIN+RAMIPRIL belongs to the group of blood pressure-lowering medications called 'Angiotensin-Converting Enzyme (ACE) Inhibitors' primarily used to treat high blood pressure (hypertension) and reduce the risk of having a heart attack, stroke, or heart failure. Besides this, it also lowers the raised level of bad cholesterol (especially those at high risk of heart diseases). High blood pressure is a chronic condition in which the pressure in the blood vessels is high. The blood exerts a high pressure on the walls of blood vessels (arteries), leading to hypertension. Heart failure can occur when your heart is unable to pump blood sufficiently required to the remaining of the body. A heart attack is the blockage of blood flow to the heart muscle.  The blockage is most often a build-up of fat, cholesterol, and other substances, which form a plaque in the arteries that feed the heart (coronary arteries).  Heart attack and brain stroke happen simultaneously as in stroke blood supply to the brain get interrupted causing a part of the brain to die.

ATORVASTATIN+RAMIPRIL is composed of two medicines, namely: Atorvastatin and Ramipril. Atorvastatin is a cholesterol-lowering medication that blocks the enzyme required to make fat in the body. It reduces the bad cholesterol (also known as low-density lipoproteins or LDL), triglycerides (TG) and increases the levels of good cholesterol (also known as high-density lipoproteins or HDL).  Ramipril is an angiotensin-converting enzyme or ACE inhibitors that lower increased blood pressure by blocking a naturally occurring substance known as angiotensin II that tightens your blood vessels thereby relaxing blood vessel in the body which reduces overload on the heart to pump more blood. Together ATORVASTATIN+RAMIPRIL reduces the risk of heart attack, stroke, and heart-related chest pain (angina).

Uses of Atorec R 5mg/10mg Capsule

Hypertension, Hypercholesterolemia, Prevention of heart attack, Prevention of stroke

Medicinal Benefits of Atorec R 5mg/10mg Capsule

ATORVASTATIN+RAMIPRIL is composed of two medicines, namely: Atorvastatin and Ramipril. Atorvastatin is a cholesterol-lowering medication that blocks the enzyme required to make fat in the body. It reduces the bad cholesterol (also known as low-density lipoproteins or LDL), triglycerides (TG) and increases the levels of good cholesterol (also known as high-density lipoproteins or HDL).  Ramipril is an angiotensin-converting enzyme or ACE inhibitors that lower increased blood pressure by blocking a naturally occurring substance known as angiotensin II that tightens your blood vessels thereby relaxing blood vessel in the body which reduces overload on the heart to pump more blood. Together ATORVASTATIN+RAMIPRIL reduces the risk of heart attack, stroke, and heart-related chest pain (angina).

Directions for Use

ATORVASTATIN+RAMIPRIL can be taken with or without food. The tablet form of ATORVASTATIN+RAMIPRIL should be swallowed as a whole with a glass of water, do not chew or crush it.

Side Effects of Atorec R 5mg/10mg Capsule

• Increased bleeding tendency
• Constipation
• Headache
• Muscle pain
• Weakness
• Headaches
• Decreased blood pressure
• Dizziness
• Muscle pain
• The increased blood glucose level
• Cough

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Let your doctor know if you are highly sensitive to atorvastatin, ramipril, or have any active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), pregnant or planning to become pregnant, or breastfeeding. The patient should inform the doctor that they are taking ATORVASTATIN+RAMIPRIL before any surgery is scheduled or any new medicine is taken. Atorvastatin present in ATORVASTATIN+RAMIPRIL is a pregnancy category X drug, so it is contraindicated in pregnant women. As it may cause harm to the fetus if administered to a pregnant woman. Co-administration with anticoagulants like warfarin may cause gastric bleeding and other bleeding problems. So, if you are using any blood-thinning agents, let your doctor know about this. ATORVASTATIN+RAMIPRIL contains Atorvastatin which can cause muscle problems like myopathy and rhabdomyolysis. So, any signs of muscle pain, tenderness, or weakness, during the initial months of the treatment should be closely monitored. Patients with active liver disease should use ATORVASTATIN+RAMIPRIL with caution. Safety and effectiveness of ATORVASTATIN+RAMIPRIL have not been established, so its use should be avoided in pediatric patients or children less than 12 years of age. Discontinuation of ATORVASTATIN+RAMIPRIL may lead to cardiovascular events like heart attack, stroke, and angina (heart-related chest pain). Hence, you should consult a doctor before stopping the dose of ATORVASTATIN+RAMIPRIL. 

Drug Interactions

Drug-Drug Interaction:

ATORVASTATIN+RAMIPRIL interacts with ATORVASTATIN+RAMIPRIL, so it should be used with caution with an antibiotic (clarithromycin), anti-HIV drugs (ritonavir, lopinavir, darunavir, atazanavir, indinavir) and antifungal (itraconazole), blood thinners (warfarin, heparin), anti-arthritis drug (colchicine), heart-related medicine (digoxin), and immune system affecting drug (cyclosporine).

Drug-Disease Interaction:

 ATORVASTATIN+RAMIPRIL should not be given to the patients with active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), muscle problems or musculoskeletal problems (myopathy, rhabdomyolysis), asthma, purpura (blood leakage under the skin), patients with nil urine output (anuria), cardiogenic shock (when the heart fails to pump required blood to the body),  low blood pressure (hypotension), coronary heart disease, heart failure, high serum potassium (hyperkalemia), patients with nil urine output (anuria). 

Safety Advice

ALCOHOL

ATORVASTATIN+RAMIPRIL should not be taken until prescribed if you are taking alcohol. Keep your doctor informed if you drink alcohol. Drinking alcohol with ATORVASTATIN+RAMIPRIL may potentiate gastric or stomach bleeding and ulcer symptoms. So, try to avoid or limit the consumption of alcoholic beverages while using ATORVASTATIN+RAMIPRIL.

PREGNANCY

ATORVASTATIN+RAMIPRIL contains Atorvastatin, which is a pregnancy category X medicine. So, it is not recommended for the pregnant mother or those who are planning to get pregnant. In an extreme case, your doctor will decide whether ATORVASTATIN+RAMIPRIL can be given or not.

BREAST FEEDING

Take ATORVASTATIN+RAMIPRIL only when prescribed, as it is known to pass on in a limited quantity via breast milk to the child. Contact your doctor before using ATORVASTATIN+RAMIPRIL.

DRIVING

Drive with caution as ATORVASTATIN+RAMIPRIL can cause dizziness and may affect your driving ability.

LIVER

ATORVASTATIN+RAMIPRIL to be taken with caution, especially if you have a history of liver diseases/conditions. The dose will be adjusted by your doctor.

KIDNEY

ATORVASTATIN+RAMIPRIL to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose will be adjusted by your doctor.